Cart
sales@molnova.com
CYM 5520
CAS No. 1449747-00-5
CYM 5520( —— )
Catalog No. M23616 CAS No. 1449747-00-5
noncompetitive allosteric agonist of S1P2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | In Stock |
|
| 5MG | 86 | In Stock |
|
| 10MG | 131 | In Stock |
|
| 25MG | 237 | In Stock |
|
| 50MG | 354 | In Stock |
|
| 100MG | 528 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCYM 5520
-
NoteResearch use only, not for human use.
-
Brief Descriptionnoncompetitive allosteric agonist of S1P2.
-
Descriptionnoncompetitive allosteric agonist of S1P2.
-
In Vitro——
-
In VivoAnimal Model:Ovariectomized 12 weeks old C57Bl6J mice Dosage:10 mg/kg.Administration:i.p.; 5 consecutive days per week; for 6 weeks Result:Corrected ovariectomy-induced osteopenia in mice by inducing new bone formation.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetS1P Receptor
-
RecptorS1P2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1449747-00-5
-
Formula Weight345.4
-
Molecular FormulaC21H19N3O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:≤30mg/ml
-
SMILESCC1=CC(=C(N1CC2=CC=CC=C2)C)C(=O)CN3C=C(C=CC3=O)C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Satsu H , Schaeffer M T , Guerrero M , et al. A sphingosine 1-phosphate receptor 2 selective allosteric agonist[J]. Bioorganic & Medicinal Chemistry, 2013, 21( 17):5373-5382.
molnova catalog
related products
-
Vibozilimod
Vibozilimod (SCD-044) is S1P receptor-1 (S1PR1) agonist .
-
TY-52156
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM). TY-52156 displays submicromolar potency and a high degree of selectivity for the S1P3 receptor.
-
JTE-013
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).JTE-013 is a S1P2 antagonist. JTE-013 (50-200 μM;?1-3 days) decreased cell viability.
